What is Rejuran?
Rejuran® is an advanced skin rejuvenation injectable treatment made from polynucleotides (PNs) — powerful DNA fragments derived from salmon that help repair and heal the skin at a cellular level. Also known as “skin healer” or “baby skin injection,” Rejuran is ideal for improving skin texture, reducing sensitivity, and reversing signs of damage.
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• How does Rejuran work and what does it treat? READ MORE >
• What are the benefits of Rejuran? READ MORE >
• Are there any side effects and what is post-treatment aftercare? READ MORE >
• How often should I have Rejuran and how long does it last? READ MORE >
• Rejuran vs Profhil vs Sculptra READ MORE >
• Is Rejuran right for you and is it safe? READ MORE >
How does Rejuran work and what does it treat?
How does Rejuran work?
Rejuran contains polynucleotides (PN), which are biocompatible molecules with remarkable skin-repairing abilities. When injected into the dermis, they:
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Stimulate cell regeneration
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Improve skin barrier function
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Enhance collagen and elastin production
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Reduce inflammation and sensitivity
Rejuran does not volumize or hydrate like fillers — instead, it restores skin health, making it stronger, smoother, and more youthful over time.
Rejuran is administered using a series of tiny injections placed just beneath the surface of the skin. Immediately after treatment, you’ll notice small, raised bumps (like tiny mosquito bites) across the treated area. These bumps are temporary and typically settle within 24 to 48 hours.
As your skin absorbs the polynucleotides, cellular repair begins, helping to strengthen the skin’s structure, improve texture, and enhance its overall health and appearance
What can Rejuran treat?
Rejuran is especially effective for clients with weakened, damaged, or sensitive skin. It is commonly used for:
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Dark circles and under-eye crepiness
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Acne scars and enlarged pores
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Thin, fragile or irritated skin
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Fine lines and early signs of ageing
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Post-laser or microneedling recovery support
What are the benefits of Rejuran?
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Repairs and strengthens skin barrier
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Improves texture, tone and elasticity
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Calms redness and reduces inflammation
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Safe for sensitive and acne-prone skin
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Can be used on face, neck, eyes or scars
Are there any side effects and what is the post-treatment aftercare?
Are there any side-effects?
Rejuran is very gentle and well tolerated. As with all injectable treatments, you may experience:
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Mild swelling or small bumps at injection points (usually resolve in 24–48 hours)
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Slight redness or pinpoint bruising
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Tingling or tightness in the treated area (temporary)
These effects are generally short-lived and are part of the healing response.
What is the post-treatment aftercare?
To support skin healing, follow these simple aftercare steps:
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Avoid makeup and skincare for 12 hours
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No facial treatments, sauna, or intense exercise for 3 days
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Use gentle, hydrating skincare
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Apply sunscreen daily to protect healing skin
Find out how often you can have Rejuran and how long it lasts >
How often should I have Rejuran and how long does it last?
How often should I have Rejuran?
A typical Rejuran program includes:
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3 sessions, spaced 2 to 4 weeks apart
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Maintenance every 4 to 6 months for ongoing skin regeneration
Your personalised plan will depend on your skin condition and goals.
How long does it last?
Skin improvements can be seen within 2–4 weeks after your first session, with continued results as collagen regenerates. After a full course, benefits can last up to 6–9 months with proper maintenance.
Rejuran vs Profhilo vs Sculptra
Rejuran
Main Ingredient
Polynucleotides (PNs from salmon DNA)
Primary Action
Skin healing + regeneration
Result
Improved skin texture, scars, sensitivity
Best for
Sensitive, acne-prone, or damaged skin
Treatment Areas
Face, neck, under-eyes
Onset of Results
2–4 weeks with consistent sessions
Maintenance
Monthly for 3–4 sessions, then as needed
Profhilo
Main Ingredient
Hyaluronic Acid (HA)
Primary Action
Deep hydration + collagen stimulation
Result
Glowing, plump, hydrated skin
Best for
Dull, dry, crepey skin
Treatment Areas
Face, neck, hands, décolletage
Onset of Results
3–4 weeks after 2 sessions
Maintenance
Every 6 months
Sculptra
Main Ingredient
Poly-L-lactic acid (PLLA)
Primary Action
Collagen stimulation + gradual volume
Result
Lifting, firming, and long-term volume
Best for
Volume loss, sagging, deep folds
Treatment Areas
Face, temples, jawline, body
Onset of Results
Gradual over 6–12 weeks
Maintenance
Every 1–2 years
Is Rejuran right for you and is it safe?
Is Rejuran right for you?
If your skin feels tired, sensitive, acne-prone, or scarred — Rejuran offers a gentle but powerful way to restore a healthy, smooth, and resilient complexion from within.
Book a skin consultation with Nurse Wei at WeiBetter Cosmetic Clinic and find out if Rejuran is the right treatment to restore your glow.
Common treatment areas include:
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Under the eyes (to treat fine lines or dark circles)
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Entire face
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Neck
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Décolletage (upper chest)
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It’s an ideal choice for anyone wanting to improve overall skin quality, particularly if you experience sensitivity, redness, or inflammation.
Is Rejuran Safe?
Rejuran treatments are generally very safe. The main visible effect is the raised bumps immediately after injection, which fade within 24–48 hours. Unlike dermal fillers, serious risks like vascular occlusions or blindness are not associated with polynucleotides.
Rejuran has been trusted in aesthetic medicine across Asia since 2014, with over 10 million treatments performed worldwide.
At WeiBetter Cosmetic Clinic, we’ll guide you through pre-treatment and aftercare instructions to ensure a smooth recovery and optimal results.